The Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) is a public-private NSF center that helps companies address technical challenges via scalable lab-on-a-chip technology. Through productive, meaningful partnerships between universities and industry, we develop microscale tools and technologies aimed at simpler, faster, and cheaper analytical solutions addressing human health, agriculture, and the environment. Join us and realize key benefits regarding first access to cutting-edge lab-on-a-chip research, recruiting, and relationship building.

Next CADMIM Industrial Advisory Board meeting will be held virtually the week September 8 – 10, 2020.
Agenda here: https://www.inrf.uci.edu/cadmim/iabmeeting/agenda/

This short video, produced by UIDP and featuring CADMIM, presents an overview of the National Science Foundation (NSF) Industry-University Cooperative Research Center (IUCRC) program and how these unique centers operate, contribute to the nation’s research infrastructure base, facilitate technology transfer, and enhance the intellectual capacity of the science and engineering workforce through the integration of research and education.


“Our CADMIM membership is pivotal in building a network with world leading experts in microfluidics. CADMIM enabled us to conduct research projects at the transition from basic research to industrial application expanding our capabilities far beyond internal expertise. Combined with the focus on manufacturability the center offers a unique set of expertise and opportunities.”
– Dr. Frank Narz, Director R&D Scientific Applications, QIAGEN GmbH

“CADMIM offers a unique blend of university research from leading researchers in the field supported by leading providers of microfluidic manufacture and development. For the industrial members of CADMIM, who are interested in new product opportunities, this means novel IP is quickly reduced to practice for real world applications.”
– Dr. Leanna Levine, Founder, President and CEO, ALine, Inc.

“With tight research budgets, CADMIM offers an opportunity to leverage industrial investments. We’ve been able to guide world-class research in microfluidics toward challenges in technology development that are barriers to transition. Working in partnership with other members of the industrial advisory board has also brought valuable insight to our programs.”
– Dr. Laura Rea, Program Manager, Soft Matter Materials Branch, Air Force Research Laboratory


CADMIM Research Groups Receive Outstanding Paper Awards
The research groups of Dr. Abe Lee (Center Director) and Dr. Ian Papautsky (Center Co-Director) have each received Outstanding Paper Awards from Microsystems and Nanoengineering. Congratulations to both! Full list of awardees: Awardees List

  • “Whole-Blood Sorting, Enrichment, and In-situ Immunolabeling of Cellular Subsets using Acoustic Microstreaming” by Neha Garg, Trisha M. Westerhof, Vick Liu, Robin Liu, Edward L. Nelson, Abe Lee. Publication link
  • “Isolation of Circulating Tumor Cells in Non-small-cell-lung-cancer Patients using a Multi-flow Microfluidic Channel,” by Jian Zhou, Arutha Kulasinghe, Amanda Bogseth, Ken O’Byrne, Chamindie Punyadeera, Ian Papautsky. Publication link

CADMIM Featured in Chemical Engineering Progress
An article entitled “Catalyzing Commercialization: Microfluidics-Based Chips Simplify Single-Cell Separations for Clinical Research” was published in the July 2020 issue of Chemical Engineering Progress (CEP). This article describes the tissue dissociation platform developed in the laboratory of Dr. Jered Haun, CADMIM Core faculty member. This work was selected by NSF to be featured in CEP, and is part of an on-going series highlighting NSF-funded breakthroughs from IUCRCs. UCI’s Henry Samueli School of Engineering posted a related news article entitled “NSF Highlights Haun’s Tissue Dissociation Technology as Breakthrough.” Access CEP article here: CEP CADMIM article. Access UCI article here: UCI HSSoE News Article

CADMIM Contributions to Lab on a Chip
Abe Lee, CADMIM Director and Lab on a Chip editor-in-chief, published a perspective article for this journal commemorating its 20th anniversary. The article is entitled “2020 vision: celebrating the 20th year of Lab on a Chip.” Access it here: Abe Lee LOC article. Dr. David Eddington, CADMIM Core Faculty member at University of Illinois at Chicago, was named an Outstanding Reviewer of Lab on a Chip, as selected by the editorial team for his significant contribution to this journal. Complete list here: Lab on a Chip Outstanding Reviewers. Ian Papautsky (CADMIM Co-Director, UIC) and Michelle Khine (CADMIM faculty member, UCI) have been selected for the 2020 Lab on a Chip Advisory Board. See complete list here: Lab on a Chip 2020 Advisory Board

Digman Lab Publishes in Nature Cell Biology
The laboratory of Dr. Michelle Digman, CADMIM Core Faculty at UCI, has co-authored a new publication in Nature Cell Biology. Dr. Francesco Palomba, post-doc in the Digman lab and contributor to CADMIM project Y6-004: “Compound Screening of Cell-Cell Pairing” is also a co-author. The paper entitled “Biophysical Properties of AKAP95 Protein Condensates Regulate Splicing and Tumorigenesis” was published July 27, 2020. Full author list: Wei Li, Jing Hu, Bi Shi, Francesco Palomba, Michelle Digman, Enrico Gratton, Hao Jiang. Congratulations to the team! Access paper here: https://www.nature.com/articles/s41556-020-0550-8

Alireza Ahmadian Yazdi = Dean’s Scholar Fellowship Recipient
Congratulations to Alireza Ahmadian Yazdi! Ali is a graduate student in the laboratory of Dr. Jie Xu, CADMIM core faculty member at University of Illinois at Chicago (UIC). Ali will be a recipient of the Dean’s Scholar Fellowship for the 2020-2021 academic year. The Dean’s Scholar Fellowship is a one-year, non-renewable award presented by the Dean of the Graduate College in recognition of a student’s scholarly achievement. This fellowship is one of the most distinguished and competitive awards that UIC offers to graduate students. Those chosen are the students considered most promising, and most likely to make outstanding contributions to this institution and their fields of learning.

New CADMIM PhD = Dr. Jeremy Lombardo
Congratulations to Dr. Jeremy Lombardo in the research group of Dr. Jered Haun (CADMIM Core Faculty) at UC Irvine. He successfully defended his dissertation entitled “Microfluidic tissue dissociation platform for single cell analysis and therapeutic applications” on July 17, 2020. Dr, Lombardo was a contributor to CADMIM projects Y6-005: “Device Design and Protocol Optimization for Dissociation of Diverse Tissues and Organs into Single Cells” and N-005: “Integrated Tumor Tissue Processing Chip to Generate Single Cells.”

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