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Welcome!

Thank you for visiting the Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM). We are a National Science Foundation (NSF) Industry/University Cooperative Research Center (I/UCRC). Our mission is to develop design tools and manufacturing technologies for integrated microfludics targeting cost-effective, quick, and easy assessment of the environment, agriculture, and human health. Get involved in this world-class, cutting-edge NSF I/UCRC! Join our organization and reap the many benefits.

For a 1-page summary of the CADMIM mission and vision, download the following document: CADMIM_Mission_Vision_statement

Check out our LinkedIn page! CADMIM LinkedIn

Download brochure about CADMIM here (front side shown below): CADMIM brochure

brochure

Testimonials

“Our CADMIM membership is pivotal in building a network with world leading experts in microfluidics. CADMIM enabled us to conduct research projects at the transition from basic research to industrial application expanding our capabilities far beyond internal expertise. Combined with the focus on manufacturability the center offers a unique set of expertise and opportunities.”
– Dr. Frank Narz, Director R&D Scientific Applications, QIAGEN GmbH

“CADMIM offers a unique blend of university research from leading researchers in the field supported by leading providers of microfluidic manufacture and development. For the industrial members of CADMIM, who are interested in new product opportunities, this means novel IP is quickly reduced to practice for real world applications.”
– Dr. Leanna Levine, Founder, President, and CEO of ALine, Inc.


News

The next CADMIM IAB meeting will be held March 1 – 2, 2017 at UC Irvine.
Meeting agenda here: Agenda
Travel information and logistics here: Logistics

Abe Lee now Editor-in-Chief for Lab on a Chip Journal
Abe Lee, CADMIM Center Director, has accepted a4-year appointment as the next Editor-in-Chief for the Lab on a Chip (LOC) journal (Royal Society of Chemistry). He is replacing Prof. George Whitesides at Harvard starting January 1, 2017. Lab on a Chip is arguably the most influential and reputable journal in the microfluidics field (current impact factor 5.7 and was as high as 7.2 in recent years). Abe is in the process of revamping the editorial board and preparing Thematic Issues from leading opinion leaders in the field. The vision is to build on the leadership position LOC has already established and broaden the scope to become the elite journal at the interface between physical technological advancements and high impact applications that are of direct interest to a broad audience. Congratulations Abe!
UCI on-line article with additional details:
http://engineering.uci.edu/news/2016/12/bme-chair-named-loc-editor-chief
Official announcement published in Lab on a Chip December 2016: LOC_editor_news_2017
Lab on a Chip blog announcement: Lab on a Chip Blog

CADMIM Students Take 3rd Prize at 9th Annual Art in Science Competition
Neha Garg and Dylan Boyle, graduate students in Abe Lee’s lab, won third place at the UCI Art in Science competition, sponsored by The Optics Society and the Beckman Laser Institute November 17th, 2016. There were about 30 entries in the competition, with most entries focusing on interesting micro-scale environments. Neha and Dylan placed with an artisitc photo of green flourescent microparticles trapped in on-chip vortices. The photo is taken with a long exposure, to show the path lines of the particles. The larger fluorescent particles (15 micron) can be selectively separated based on size from small particles (10 micron), using lateral cavity acoustic transducers (LCATs). Researchers in Dr. Lee’s lab are working to utilize such trapping in the isolation of rare cells, such as circulating tumor cells, for patient point-of-care.

Michelle Khine Included in 2016 Class of National Academy of Inventors Fellows
Dr. Michelle Khine is one of 2 professors from UC Irvine named fellows of the National Academy of Inventors for 2016. The distinction is awarded to academics who have demonstrated a prolific spirit of innovation with outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. There are now 757 NAI fellows, representing 229 research universities and governmental and nonprofit research institutes. Michelle will be inducted on April 6, 2017, as part of the Sixth Annual Conference of the National Academy of Inventors in Boston. Congratulations Michelle!
UCI on-line article with additional details: National Academy of Inventors Article

IAB Meeting held at the University of Cincinnati September 2016
Great seeing everyone at the University of Cincinnati for the Fall 2016 IAB meeting! Meeting materials are posted on the secure website. For more photos from this event see here:
Meeting and poster session photos Sept. 2016

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Click to enlarge!

CADMIM featured in 2016 NSF Compendium – Technology Breakthrough
The results from project “Integrated Microfluidic Device for Isolation & Enrichment of Rare Cells,” led by Abraham Lee and Ian Papautsky, are featured in 2016 NSF Compendium for Industry-Nominated Technology Breakthroughs! The compendium lists projects embarked on by 33 Industry & University Cooperative Research Centers (I/UCRCs) nationwide expected to result in technological breakthroughs – process improvements or techniques, new products or services and/or benefits to the nation’s economy. The publication is intended to help Congressional and White House staffers, NSF visitors and the general public understand the impact of research taking place at the country’s I/UCRCs.

This is a major achievement for CADMIM – the average age of the 33 I/UCRCs featured in 2016 Compendium is 8 yrs old (by comparison, CADMIM is only 2 years old!). This achievement is featured on the UCI Samueli School of Engineering website: CADMIM Technology Breakthrough
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CADMIM Provisional Patent
The project “Y2-002: NFC-Operated Quantitative Point-of-care Diagnostic Assays with Low-to-Zero On-Board Power,” led by Andrew Steckl at U. Cincinnati has resulted in a provisional patent entitled “Integrated NFC Power Source for Zero On-Board Power in Fluorescent Paper-based Lateral Flow Immunoassays,” Docket Number 116-078-UC, filed June 16, 2016. The inventors are: Andrew Steckl (U. Cincinnati), Vishak Venkatraman (U. Cincinnati), Ralph Liedert (VTT Technical Research Center Finland). Congratulations to the team!
Click here for 1-page summary of this invention and licensing officer contact information: 1pg summary-NFC Powered Medical Device [116-078] Andrew_ROI

CADMIM Captures additional NSF funding
Congratulations to Jason Heikenfel for capturing additional funds for the wearable sweat sensor work. Various aspects of this research has been funded through CADMIM. Details on this recent award below:

Congratulations to Abe Lee and Ian Papautsky for capturing additional funds for the CADMIM project that combined two microfluidic components for the selective isolation and enrichment of rare cells from whole blood – an inertial microfluidic (iMF) component developed by Ian Papautsky’s group at U. Cincinnati, and a lateral cavity acoustic transducer (LCAT) component developed by Abe Lee’s group at UC Irvine. This project was previously seeded at CADMIM. Details on this recent award below:

  • Partnerships for Innovation: Accelerating Innovation Research – Technology Translation (PFI:AIR-TT)
  • PI: Abe Lee (UCI), Co-PI: Ian Papautsky (U. Cinn.), Industry Partner = Qiagen
  • “Integrated Microfluidic System for Cell Separation and Enrichment”
  • $200K for 18 months from NSF
  • Start date May 1, 2016
  • Project abstract can be viewed here: http://www.nsf.gov/awardsearch/showAward?AWD_ID=1604014&HistoricalAwards=false

News articles about CADMIM
Since the official center launch in April 2014, CADMIM has gained exposure through several news articles:
(1) University of California, Irvine, School of Engineering News:
UCI Engineering News
(2) University of Cincinnati News: U. Cincinnati News
(3) Lab on a Chip announcement: Lab-on-a-Chip News. PDF version here:
Lab-on-a-Chip News (PDF)