Thank you for visiting the Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM). We are a National Science Foundation (NSF) Industry/University Cooperative Research Center (I/UCRC). Our mission is to develop design tools and manufacturing technologies for integrated microfludics targeting cost-effective, quick, and easy assessment of the environment, agriculture, and human health. Get involved in this world-class, cutting-edge NSF I/UCRC! Join our organization and reap the many benefits.

For a 1-page summary of the CADMIM mission and vision, download the following document: CADMIM_Mission_Vision_statement

Check out our LinkedIn page! CADMIM LinkedIn

Download a brochure about CADMIM here (front side shown below): CADMIM brochure



The next CADMIM IAB meeting will be held February 22 – 23, 2017 at UC Irvine. Please save the date!

IAB Meeting held at the University of Cincinnati
Great seeing everyone at the University of Cincinnati for the Fall 2016 IAB meeting! Meeting materials are posted on the secure website. For more photos from this event see here:
Meeting and poster session photos Sept. 2016


Click to enlarge!

CADMIM featured in 2016 NSF Compendium – Technology Breakthrough
The results from project “Integrated Microfluidic Device for Isolation & Enrichment of Rare Cells,” led by Abraham Lee and Ian Papautsky, are featured in 2016 NSF Compendium for Industry-Nominated Technology Breakthroughs! The compendium lists projects embarked on by 33 Industry & University Cooperative Research Centers (I/UCRCs) nationwide expected to result in technological breakthroughs – process improvements or techniques, new products or services and/or benefits to the nation’s economy. The publication is intended to help Congressional and White House staffers, NSF visitors and the general public understand the impact of research taking place at the country’s I/UCRCs.

This is a major achievement for CADMIM – the average age of the 33 I/UCRCs featured in 2016 Compendium is 8 yrs old (by comparison, CADMIM is only 2 years old!). This achievement is featured on the UCI Samueli School of Engineering website: CADMIM Technology Breakthrough

Papautsky & VTT Cover Article
Recent publication on roll-to-roll manufacturing of inertial devices entitled “A Disposable, Roll-to-roll Hot-embossed Inertial Microfluidic Device for Size-based Sorting of Microbeads and Cells” in collaboration with VTT Technical Research Center in Finland appeared on line in the April 6, 2016 issue of Lab on a Chip as well as the back cover of the May 21, 2016 print issue (below).
Papautsky_2016_LOC_Backcover This work  was also the subject of an editorial by Mr. Cesar M. Castro entitled “Extra! Extra! Microfluidic chips go to print!” which appears in Science Translational Medicine, Vol. 8, Issue 337, pp. 337ec72, DOI: 10.1126/scitranslmed.aaf8774. See the editorial here: http://stm.sciencemag.org/content/8/337/337ec72. Congratulations Ian and VTT!

CADMIM Provisional Patent
The project “Y2-002: NFC-Operated Quantitative Point-of-care Diagnostic Assays with Low-to-Zero On-Board Power,” led by Andrew Steckl at U. Cincinnati has resulted in a provisional patent entitled “Integrated NFC Power Source for Zero On-Board Power in Fluorescent Paper-based Lateral Flow Immunoassays,” Docket Number 116-078-UC, filed June 16, 2016. The inventors are: Andrew Steckl (U. Cincinnati), Vishak Venkatraman (U. Cincinnati), Ralph Liedert (VTT Technical Research Center Finland). Congratulations to the team!
Click here for 1-page summary of this invention and licensing officer contact information: 1pg summary-NFC Powered Medical Device [116-078] Andrew_ROI

Slapband Vitals on America’s Greatest Makers
Nicole Mendoza and Kim Veliz, students in Michelle Khine’s lab at UCI, have not only started a new company called Slapband Vitals, but they were also contestants on the TV reality show America’s Greatest Makers. United Artist CEO Mark Burnett, the producer behind popular shows like “Survivor,” “Shark Tank,” “The Apprentice,” and “The Voice,” launched America’s Greatest Makers, a reality show that premiered April 5th on TBS and follows 24 teams competing for a $1 million prize.  Nicole and Kim have been working together in the Khine lab to develop a sensor-based wearable wristband that provides immediate and continuous monitoring of your vitals associated with blood pressure. They started Slapband Vitals to commercialize this product. Way to go Slapband!
SlapbandTo see the America’s Greatest Makers profile on this start-up (with videos and interviews) see here: https://www.americasgreatestmakers.com/team/slapband/
For an on line article in UCI’s Engineering News about the team and the show:

CADMIM Captures additional NSF funding
Congratulations to Jason Heikenfel for capturing additional funds for the wearable sweat sensor work. Various aspects of this research has been funded through CADMIM. Details on this recent award below:

Congratulations to Abe Lee and Ian Papautsky for capturing additional funds for the CADMIM project that combined two microfluidic components for the selective isolation and enrichment of rare cells from whole blood – an inertial microfluidic (iMF) component developed by Ian Papautsky’s group at U. Cincinnati, and a lateral cavity acoustic transducer (LCAT) component developed by Abe Lee’s group at UC Irvine. This project was previously seeded at CADMIM. Details on this recent award below:

  • Partnerships for Innovation: Accelerating Innovation Research – Technology Translation (PFI:AIR-TT)
  • PI: Abe Lee (UCI), Co-PI: Ian Papautsky (U. Cinn.), Industry Partner = Qiagen
  • “Integrated Microfluidic System for Cell Separation and Enrichment”
  • $200K for 18 months from NSF
  • Start date May 1, 2016
  • Project abstract can be viewed here: http://www.nsf.gov/awardsearch/showAward?AWD_ID=1604014&HistoricalAwards=false

News articles about CADMIM
Since the official center launch in April 2014, CADMIM has gained exposure through several news articles:
(1) University of California, Irvine, School of Engineering News:
UCI Engineering News
(2) University of Cincinnati News: U. Cincinnati News
(3) Lab on a Chip announcement: Lab-on-a-Chip News. PDF version here:
Lab-on-a-Chip News (PDF)