Home

Welcome!

Thank you for visiting the Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM). We are a National Science Foundation (NSF) Industry/University Cooperative Research Center (I/UCRC). Our mission is to develop design tools and manufacturing technologies for integrated microfluidics targeting cost-effective, quick, and easy assessment of the environment, agriculture, and human health. Get involved in this world-class, cutting-edge NSF I/UCRC! Join our organization and reap the many benefits.

Check out our LinkedIn page! CADMIM LinkedIn

Left: Dr. Ian Papautsky (CADMIM Center Co-Director and University of Illinois Chicago Site Leader).
Right: Dr. Abraham Lee (CADMIM Center Director and University of California Irvine Site Leader)


Testimonials

“Our CADMIM membership is pivotal in building a network with world leading experts in microfluidics. CADMIM enabled us to conduct research projects at the transition from basic research to industrial application expanding our capabilities far beyond internal expertise. Combined with the focus on manufacturability the center offers a unique set of expertise and opportunities.”
– Dr. Frank Narz, Director R&D Scientific Applications, QIAGEN GmbH

“CADMIM offers a unique blend of university research from leading researchers in the field supported by leading providers of microfluidic manufacture and development. For the industrial members of CADMIM, who are interested in new product opportunities, this means novel IP is quickly reduced to practice for real world applications.”
– Dr. Leanna Levine, Founder, President and CEO, ALine, Inc.

“With tight research budgets, CADMIM offers an opportunity to leverage industrial investments. We’ve been able to guide world-class research in microfluidics toward challenges in technology development that are barriers to transition. Working in partnership with other members of the industrial advisory board has also brought valuable insight to our programs.”
– Dr. Laura Rea, Program Manager, Soft Matter Materials Branch, Air Force Research Laboratory


News

Our First CADMIM IAB meeting at UIC!
The Fall Industrial Advisory Board meeting was held at the University of Illinois Chicago September 12 – 13, 2017. Great seeing everyone in the windy city! Students and post-docs updated everyone on project progress, and we welcomed UIC faculty and students to the center. We look forward to spending more time in Chicago in the years to come! See photos from this event here: http://www.inrf.uci.edu/cadmim/about-cadmim/photos/

Many thanks to UIC for hosting a great IAB meeting! Click photo to enlarge.

CADMIM Participates in 2017 NSF I/UCRC Biennial Meeting
CADMIM had strong representation at the NSF I/UCRC Biennial Meeting held July 26 – 28, 2017 in Arlington, VA. This meeting provided an opportunity for I/UCRC Directors, Operations Personnel, Assessment Coordinators, NSF I/UCRC program staff, and other stakeholders to interact and exchange ideas to promote center improvement, growth, and collaboration. CADMIM students from both sites (Erik Werner from UC Irvine and Prithviraj Mukherjee from U. Illinois Chicago) presented our center poster at the poster session in the evening July 26. Both students also participated in the first ever Innovation Pitch Student Competition at this event. Abe Lee, CADMIM Center Director, was a panelist July 27 at the “Multi-Site Center” breakout session. Abe shared our experience in fostering collaborations between faculty, and got many questions about how to make this work.
Event website: http://www.nsfiipconf.com/2017iucrc/

   
(Left) Erik Werner and Prithviraj Mukherjee present CADMIM’s poster.
(Right) Abe Lee speaking at the “Multi-Site Center” panel.

New Inside Cover Article in Lab on a Chip from CADMIM
Congratulations to Zachary Sonner, Eliza Wilder, Trudy Gaillard, Gerald Kasting, and Jason Heikenfeld! Their manuscript entitled “Integrated Sudomotor Axon Reflex Sweat Stimulation for Continuous Sweat Analyte Analysis with Individuals at Rest” was published in the August 7, 2017 issue Lab on a Chip. This paper was also selected as the inside cover article! It is available on line here: http://pubs.rsc.org/en/content/articlelanding/2017/lc/c7lc00364a#!divAbstract. This work is a direct result of CADMIM-funded project Y2-004 entitled “World’s 1st Sweat Stimulation and Sensing Patch! + No Interference! + 170% FOM!” (funded at CADMIM 2015 – 2016).

New Cover Article in Analyst from CADMIM
Congratulations to Nivedita Nivedita, Neha Garg, Abe Lee, and Ian Papautsky! Their manuscript entitled “A High Throughput Microfluidic Platform for Size-selective Enrichment of Cell Populations in Tissue and Blood Samples” was published in the July 21, 2017 issue of Analyst. This paper was also selected as the cover article! It is available on line here: http://pubs.rsc.org/en/content/articlelanding/2017/an/c7an00290d#!divAbstract. This work is a direct result of CADMIM-funded project ES-006 entitled “Intermediate-Scale Manufacturing for Sample Enrichment and Concentration” (funded at CADMIM 2014 – 2016).

Second Site of CADMIM Officially Moved to UIC
As of June 2017 the University of Illinois Chicago (UIC) has officially become the second site of CADMIM, under the site leadership of Dr. Ian Papautsky. Although the process of moving the site from University of Cincinnati took some time, the site transfer is finally complete. We look forward to seeing the campus this Fall and learning more about the facilities and resources at UIC. U. Cincinnati will remain an affiliate university as we continue to work with Cincinnati faculty and students. An article was published about Ian’s lab in the UIC Department of Bioengineering Spring 2017 Newsletter. See here: Papautsky_lab
Dr. Papautsky was also honored as a Fellow of the Royal Society of Chemistry (RSC) in April 2017. Congratulations Ian!

Papautsky Group now at UIC Site: Jian Zhou, Ian Papautsky, Prithviraj Mukherjee

MicroTAS 2017 in Savannah, Georgia October 22- 26, 2017
This year’s 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017) will be held October 22- 26, 2017 in Savannah, Georgia. MicroTAS is the premier forum for reporting research results in microfluidics, microfabrication, nanotechnology, integration, materials and surfaces, analysis and synthesis, and detection technologies for life science and chemistry. See conference website for complete information: http://www.microtas2017.org/

On April 25, 2017, CADMIM faculty submitted 18 abstracts, including 5 based on CADMIM-funded work! As we eagerly await news of paper acceptances for oral and poster sessions, CADMIM faculty and staff have taken a prominent role in the planning of this conference:

  • Abe Lee (CADMIM Center Director) is Co-Chairing MicroTAS 2017 along with Dr. Don DeVoe (University of Maryland).
  • Ian Papautsky (CADMIM Center Co-Director) is Chair of the pre-conference Sunday Workshop (both full and half day workshops).
  • Gisela Lin (CADMIM Deputy Director) is a member of the Exhibit & Sponsorship Committee.
  • David Eddington (CADMIM Faculty member, UIC) is Chair of the Connections Committee
  • Elliot Hui (CADMIM Faculty Member, UCI) is a member of the Connections Committee.
  • Michelle Khine (CADMIM Faculty Member, UCI) is the Chair of the Shark Tank Committee (first time event at this conference!)

The exhibition hall is nearly filled with prominent companies, including IAB member ALine Inc. For a complete list of exhibitors: http://www.microtas2017.org/exhibit/booth.html. Sponsorship opportunities are still available (booths, print advertisements, Shark Tank, etc.)! Please see here to access the Exhibitor Prospectus: MicroTAS2017 Exhibitor Prospectus

Michelle Khine Selected Innovator of the Year
Dean Gregory Washington recognized 8 Samueli School of Engineering faculty members and one staff member with awards at the spring faculty meeting, June 8, 2017. Michelle Khine received the Innovator of the Year award. This award is presented to an individual or team who best demonstrates innovation in the development of a product or technology. The award recognizes achievements in which the innovation has successfully translated the research emanating from our laboratories into new products and technologies that can be used by the public at large. For more information: UCI Engineering Dean’s Awards 2017. Congratulations Michelle Khine!

Michelle Khine: 2017 UCI Samueli School of Engineering Innovator of the Year

David Eddington Captures NIH Funding
David Eddington, Associate Professor in Bioengineering at UIC and CADIMM Faculty member, just received a $416K, 2-year R21 grant from the National Institute of Health (NIH). This grant, initiated in June 2017, is entitled “Confined Genetic Transformation and Exchange of Antibiotic Resistance Genes in Femtoliter Microdroplets” and will be conducted in collaboration with Co-PI Dr. Don Morrison in the Department of Biological Sciences. This study will characterize a new mechanism of extensive horizontal gene transfer in Streptococcus pneumoniae, a major global bacterial human pathogen, causing ~1 million deaths annually worldwide due to pneumonia, sepsis, and meningitis. Microfluidics will be used to create numerous small chambers (droplets) within which attacker-target interactions can be studied and characterized for the first time at both the cellular and molecular levels, by both identifying the participant cells and tracing all gene exchange events at full genome resolution. Congratulations Dave!

Michelle Digman Also Captures NIH Funding
Dr. Michelle Digman and Dr. Ken Cho (UCI Professor in Developmental and Cell Biology) are the recipients of a new NIH R21 Multi-Principal Investigator (MPI) grant from the NICHD Eunice Kennedy Shriver National Institute of Child Health and Human Development (a division of the National Institute of Health). This 2-year, $275K grant entitled “Label Free Assessment of Embryo Vitality by the Phasor FLIM Method” will fund studies to characterize the metabolic state of the developing embryo using the phasor method to fluorescence-lifetime imaging microscopy (FLIM). The performance period is 7/1/2017-6/30/2019. Congratulations Michelle Digman!

Michelle Digman receives 2017 Hellman Fellowship Award
Dr. Michelle Digman, Assistant Professor in Biomedical Engineering and CADMIM faculty member, has received the 2017 – 2017 Hellman Fellowship. This fund was created to provide support and encouragement for the research and creative activities of promising faculty at the Assistant Professor rank, promote career advancement, and enhance the individual’s progress toward tenure. Preference in awarding Hellman Fellowships was given to faculty who show great promise in research/creative activities, have outstanding proposals, and have not received other young investigator awards. Congratulations Michelle Digman!