The Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) is a public-private NSF center that helps companies address technical challenges via scalable lab-on-a-chip technology. Through productive, meaningful partnerships between universities and industry, we develop microscale tools and technologies aimed at simpler, faster, and cheaper analytical solutions addressing human health, agriculture, and the environment. Join us and realize key benefits regarding first access to cutting-edge lab-on-a-chip research, recruiting, and relationship building.
Next CADMIM Industrial Advisory Board meeting will be held September 13 – 14, 2023 at the University of Illinois, Chicago.
This short video, produced by UIDP and featuring CADMIM, presents an overview of the National Science Foundation (NSF) Industry-University Cooperative Research Center (IUCRC) program and how these unique centers operate, contribute to the nation’s research infrastructure base, facilitate technology transfer, and enhance the intellectual capacity of the science and engineering workforce through the integration of research and education.
“Our CADMIM membership is pivotal in building a network with world leading experts in microfluidics. CADMIM enabled us to conduct research projects at the transition from basic research to industrial application expanding our capabilities far beyond internal expertise. Combined with the focus on manufacturability the center offers a unique set of expertise and opportunities.”
– Dr. Frank Narz, Director R&D Scientific Applications, QIAGEN GmbH
“CADMIM offers a unique blend of university research from leading researchers in the field supported by leading providers of microfluidic manufacture and development. For the industrial members of CADMIM, who are interested in new product opportunities, this means novel IP is quickly reduced to practice for real world applications.”
– Dr. Leanna Levine, Founder, President and CEO, ALine, Inc.
“With tight research budgets, CADMIM offers an opportunity to leverage industrial investments. We’ve been able to guide world-class research in microfluidics toward challenges in technology development that are barriers to transition. Working in partnership with other members of the industrial advisory board has also brought valuable insight to our programs.”
– Dr. Laura Rea, Program Manager, Soft Matter Materials Branch, Air Force Research Laboratory
Successful Spring CADMIM IAB Meeting
Many thanks to everyone who attended the Spring 2023 CADMIM IAB meeting! Great to see so many of you in person at the University of California, Irvine and reconnect with those who participated online. Also many thanks to all the students and post-docs who prepared posters! More photos from this event here: Feb. 2023 Meeting Photos.
Pleased to announce the new leaders of the CADMIM Industrial Advisory Board (IAB) for the 2023 – 2024 term: IAB Chair = Dr. Sarah Rue, Director of Advanced Automation Technologies at the Novartis Institutes for Biomedical Research (NIBR), and IAB Vice-Chair = Dr. Jesse Munkvold, Enabling Technologies Lead at Corteva Agriscience.
New CADMIM Member – Seed Science Foundation
Welcome to the Seed Science Foundation, our newest member of CADMIM and our first Association Member. We are very pleased that they are part of the center and we look forward to working with their delegates at upcoming CADMIM IAB virtual and in-person meetings.
The Seed Science Foundation (SSF) is a non-profit organization that addresses the needs and opportunities within the global seed industry via research and education. The SSF also seeks to provide insight and recommend solutions that enable the U.S. seed industry to function with global effectiveness. Website: https://seedsciencefoundation.org/
CADMIM at IEEE EMBS MNMC in Hawaii
Strong CADMIM representation at IEEE EMBS Micro and Nanotechnology in Medicine Conference (MNMC) in Hawaii December 5 – 9, 2022. Two presented posters were CADMIM-funded. CADMIM IAB Member, ALine Inc., also presented at poster. Total 5 oral presentations and 8 posters. Many thanks to Dr. Salman Khetani, CADMIM Core Faculty at UIC and Conference Chair (a.k.a. the Big Kahuna). CADMIM is also a proud sponsor. Had to wait 2 years for this event, but it was well worth it!
- “Physics of High-Viscosity Matrigel Droplet Generation,” Aarthi Namasivayam, Elliot Hui
- “High Aspect Ratio Glass Microstructures by Laser Induced Etching,” Jessica Cheng, Hinesh Patel, Elliot Hui
- “Membrane Integration Strategies for Microfluidic Cell Culture and Organ-on-Chip Applications,” Stefano Begolo, Leanna Levine (ALine, Inc.)
CADMIM Leaders Edit Special Issue of Micromachines
Abe Lee, CADMIM Director, Ian Papautsky, CADMIM Co-Director, and Jian Zhou, Research Assistant Professor at UIC, are guest editing a special issue of Micromachines entitled “Viscoelastic Microfluidics and Cell Sorting.” This special issue will showcase research papers, short communications, and review articles that focus on novel microfluidic approaches that utilize the properties of biological samples for high-performance cell sorting, and that investigate the fundamental physics of the cell focusing phenomena in microflows, with special emphasis on the utilization of fluid viscoelasticity for cell focusing and sorting. For more info: Micromachines Viscoelastic Microfluidics
CADMIM Ph.D. Graduates
Congratulations to Jennifer Liu (Salman Khetani’s lab), Becky Chen (Abe Lee’s lab), and Grace Brown (Salman Khetani’s lab)! All graduated with PhDs and contributed to various projects at CADMIM.
CADMIM-funded Journal Publications
- Moein Naderi, Ludovica Barilla, Jian Zhou, Ian Papautsky, Zhangli Peng, “Elasto -Inertial Focusing of Particles in Shear-Thinning Viscoelastic Fluid in Rectangular Microchannels,” Micromachines,13(12), 2131, December 2022. Access paper: Micromachines Paper
- Xuhao Luo, Abraham P. Lee, “Overcoming Double-Poisson Limitation for Co-encapsulation in Droplets through Hydrodynamic Close Packing of Cells,” Microfluidics and Nanofluidics, 27, 3 (2023), November 22, 2022. Access paper: Microfluidics and Nanofluidics
- Erik M. Werner, Benjamin Lam, Elliot E. Hui, “Phase-Optimized Peristaltic Pumping by Integrated Microfluidic Logic,” Micromachines, 13(10), 1784, Oct. 20, 2022. Access paper: https://www.mdpi.com/2072-666X/13/10/1784
- Narek E. Koucherian, Shijun Yan, Elliot E. Hui, “Fabrication of Multilayer Molds by Dry Film Photoresist,” Micromachines. 3(10), 1583; Sept. 23, 2022. Access paper: https://www.mdpi.com/2072-666X/13/10/1583
4 CADMIM Undergrads Receive REU Supplements
Two Research Experiences for Undergraduate (REU) supplements were awarded to the University of California, Irvine in Fall 2022. Aria Wang (in the laboratory of Dr. Elliot Hui, CADMIM Core Faculty) is working on a project entitled “MiniKASP Microfluidic Platform.” Chibuike Ezenekwe (in the laboratory of Dr. Michelle Digman, also CADMIM Core Faculty) is working on a project entitled “Camera-based Spectral Detection of Dipolar Relaxation in Microfluidic Controlled Gradients.”
Two additional REU supplements were awarded to the University of Illinois, Chicago in Fall 2022. Rana Abbbed (in the laboratory of Dr. David Eddington, CADMIM Core Faculty) is contributing to “Y8-004: “Reproducible Generation and Passaging of Patient-Derived Cancer Organoids.” Arman Raghian (in the laboratory of Dr. Ian Papautsky, CADMIM Co-Director) is working on a project entitled “Microfluidic Cell Culture for Precision Oncology.”