Welcome!

Thank you for visiting the official website for the Micro/Nano Fluidics Fundamentals Focus (MF3) Center. Founded in 2006, our center is composed of academic, government and commercial institutions across the country dedicated to the development of the basic science and technology of micro/nanoscale fluidics and their advancement toward applications in a number of commercial and military arenas.


Headlines:

ALine joins MF3
Welcome to ALine, Inc. who joined MF3 as a Technology member in February 2012. We are very pleased that they are part of the center and we look forward to interacting with their delegates. ALine is located in Southern California and offers cost- effective solutions for the design and manufacture of next generation diagnostic products. One of their specialties is polymer laminate technology for microfluidics. For more information, please visit the ALine website: www.alineinc.com

Elliot Hui Receives Funding from NSF
Congratulations to Dr. Elliot Hui at UC Irvine! His proposal entitled “Microfluidic Finite State Machine Controller” submitted to NSF was selected for funding in the amount of $300K over 3 years. This research activity was initially seeded by MF3 and will be part of NSF’s Integrated Hybrid Complex Systems (now called Communications, Circuits, and Sensing-Systems) under the Division of Electrical, Communications and Cyber Systems.

David Beebe and Luke Lee Receive Funding from the Gates Foundation
Announced in December 2011, both Dr. Dave Beebe (U. Wisconsin) and Dr. Luke Lee (UC Berkeley) are 2 of 22 total recipients of funding from the Bill & Melinda Gates Foundation under “Grand Challenges: Point-of-Care Diagnostics in the Developing World.” Total funding for this program is $31M. Congratulations to Dave & Luke!

Dave Beebe’s project entitled “Develop Technologies that Allow Assessment of Multiple Conditions and Pathogens at Point-of-Care” will receive $2.5M over 3 years. His group will develop a “universal” sample purification platform that readily adapts to various upstream collection components and utilizes an immiscible phase (e.g. oil, wax) barrier to produce a “clean” sample for output to downstream amplification and detection components. For more information: article link

Luke Lee’s project entitled “Integrated Microfluidic Universal Sample Preparation and Pre-concentration (USP) Module for Parallel Diagnostics of Infectious Diseases (HIV, TB and Malaria)” will receive $1.5M over 3 years. His group will develop a microfluidic sample preparation module using electrical and physical methods that will be compatible with different sample inputs and downstream analytical techniques to provide both plasma and cellular biomarkers for the parallel diagnoses of infectious diseases such as HIV, tuberculosis, and malaria. The device will not require external reagents, will have low power consumption, and can be operated on-site with minimal training. For more information: article link

Steve Wereley’s article on the Cover of Lab on a Chip (Again!)
Congratulations to Dr. Steve Wereley (Purdue University) on his second cover article in 2011. “Automated and temperature-controlled micro-PIV measurements enabling long-term-stable microchannel acoustophoresis characterization,” co-authored by Per Augustsson, Rune Barnkob, Steven Wereley, Henrik Bruus and Thomas Laurell, appears on the cover of the last issue of Lab on a Chip in 2011 (Issue 24). This article describes a platform for micro particle image velocimetry (µPIV) for analyzing two-dimensional acoustophoresis. The device is automated, temperature-stable and has uncertainties below 5% and is therefore able to conduct high-precision measurement of the acoustophoretic velocity field in microchannels.

Previously, Steve’s review article entitled “Hybrid opto-electric manipulation in microfluidics – opportunities and challenges” was selected as the cover article in the July 7, 2011, issue of Lab on a Chip. Congratulations Steve!

Latest edition of books by Dr. Marc Madou
Congratulations to Marc Madou at UCI who just published the third edition of his three-volume textbook Fundamentals of Microfabrication and Nanotechnology. “Volume 1: Solid-State Physics, Fluidics, and Analytical Techniques in Micro- and Nanotechnology” offers a rigorous theoretical treatment of micro- and nanosciences, and includes sections on solid-state physics, quantum mechanics, crystallography, and fluidics. “Volume 2: Manufacturing Techniques for Microfabrication and Nanotechnology,” an expanded version of the prior edition, presents a very large set of manufacturing techniques for micro- and nanofabrication and covers different forms of lithography, material removal processes and additive technologies. “Volume 3: From MEMS to Bio-MEMS and Bio-NEMS: Manufacturing Techniques and Applications” focuses on unique manufacturing techniques and applications of biological micro-electro-mechanical systems (Bio-MEMS) and biological nano-electro-mechanical systems (Bio-NEMS). These books are currently available through various on-line retailers.



The Micro/Nano Fluidics Fundamentals Focus Center is affiliated with several organizations at the Henry Samueli School of Engineering at U.C. Irvine, including the California Institute for Telecommunications and Information Technology (Cal-IT2) and the Integrated Nanosystems Research Facility (INRF).